ReVISION

Discover and Risk Stratify Hidden RV Dysfunction with ReVISION

Many patients with heart conditions have normal readings using standard echocardiography metrics such as TAPSE and RVEF.

A patient with shortness of breath and an atrial septal defect.

This patient has a normal TAPSE and RVEF.

Metric Value
TAPSE 25 mm
RVEF 46%

ReVISION reveals the reason for the patient's challenges, and confirms what your eyes can see.

ReVISION Metric This Patient Normal Value
Global Circ. Strain -12% below -20%

Other patients who are doing well have abnormal readings using standard 2D and 3D echocardiography metrics such as TAPSE.

A patient after heart transplant, recovering well

Although the patient appears to be doing well, and has a good RVEF, his TAPSE value is severely abnormal.

Metric Value
TAPSE 10 mm
RVEF 64%

ReVISION reveals and quantifies the reasons for the patient's good recovery and strong RVEF

ReVISION Metric This Patient Normal Value
Radial Ejection Fraction 35% 25%

ReVISION is software as a service. All you need is a web browser and a connection to the Internet. ReVISION is available for use by researchers today, and is pending FDA clearance.

ReVISION Helps You Uncover Hidden Cardiopulmonary Dysfunction

RV function can provide important diagnostic and prognostic information for patients with cardiopulmonary disease.

But unlike LV function, it has not been possible to fully characterize RV function using 3D echocardiography – until now.

ReVISION is an innovative new software technique that builds on 3D echocardiography to provide unique insights into RV function.

Developed by cardiologists like you, ReVISION is trusted by researchers in some of the world’s leading institutions.

By revealing longitudinal, radial, anteroposterior, and segmental quantitative RV metrics, ReVISION enables you to uncover hidden RV dysfunction and study its impact on cardiopulmonary health.

Accessed via our website, all you need to start assessing RV function in your next patient is their 3D echo file and a browser.

ReVISION is the only clinical solution available to quantify the longitudinal, radial and anteroposterior components of RV wall motion and also to provide segmental information based on 3D echocardiographic models.

Longitudinal Axis

Radial Axis

Longitudinal Axis

Radial Axis

Anteroposterior Axis

Segmentation

Anteroposterior Axis

Segmentation

ReVISION offers unique quantified metrics to give you a comprehensive picture of the right ventricle. These metrics provide an extra measure of confidence in even the most challenging cases.

Unique ReVISION Metrics

  • The contribution of each motion component to ejection fraction
  • Segmental analysis using a 15 segment model
  • 3D RV deformation analysis including global longitudinal and circumferential strains

Try ReVISION for yourself and see how ReVISION provides a comprehensive and quantified view of RV function.

ReVISION is available for use by researchers today, and is pending FDA clearance.

ReVISION: Trusted By More Than A Dozen Leading Institutions

Cardiology researchers at the head of their field are using ReVISION to make new discoveries every day.

ReVISION's 3 axis RV function metrics and 15 segment RV analysis allows researchers to make new discoveries about the RV and about cardiovascular health with more precision than was ever previously possible.

To read research papers published using ReVISION, please visit our publications page.

Use the 3D echo hardware you already have with ReVISION

Most cardiologists have access to 3D echo, but some have been reluctant to use it because of the limitations of RVEF and related metrics, and because of the work involved in post-processing the 3D echo data. With ReVISION, you can access much more detailed RV metrics easily, by simply uploading 3D DICOM files from your 3D echo machine to ReVISION.

3D echocardiography revolutionized the assessment of cardiac structure and function. ReVISION builds on 3D echo to better characterize right ventricular function, and the function of the entire cardiopulmonary system.

3D echocardiography-derived metrics, such as right ventricular ejection fraction (RVEF - the global measure of pump function), have been shown to be clearly superior to conventional echocardiographic measures of RV function in the prediction of adverse clinical outcomes (1) and RVEF's added value is independent of LV function (2).

Despite RVEF's power, patients with good RVEF values still experience adverse clinical events and progression of the disease course. This is true in pulmonary hypertension patients, patients undergoing cardiac interventions, congenital heart disease patients, and those who have only subtle segmental dysfunction.

RVEF describes the global function of the right ventricle, but the pattern of RV contraction can change significantly despite unchanged global function (3,4). These underlying mechanical changes hold important diagnostic and prognostic information in a variety of cardiopulmonary diseases.

ReVISION reveals underlying mechanical changes in the RV the RVEF and other conventional metrics can miss.

To try ReVISION for yourself, click to see how ReVISION provides a comprehensive and quantified view of RV function.

Pricing Plans

Basic Research

$700 / month

or

$7000 / year

User accounts that can run analyses and export data: up to 3
  • Supports 1 project with a single combined dataset

  • Supports export of analysis results in table format

  • ReVISION features enabled: all

  • Included raw 3D echo DICOM uploads per month: 12 Each additional raw 3D echo DICOM upload: $30 USD

  • TomTec 3D model uploads: Unlimited

  • Delivery: software as a service via revision.arguscognitive.com

  • 7 day risk free free trial

Clinical Trial

$4000 / month

or

$40000 / year

User accounts that can run analyses and export data: unlimited
  • Supports 1 project with a single combined dataset

  • Supports export of analysis results in table format

  • ReVISION features enabled: all

  • Coming soon: 100 raw 3D echo DICOM uploads per month included. Each additional raw 3D echo DICOM upload: $30 USD

  • TomTec 3D model uploads: Unlimited

  • Delivery: software as a service via revision.arguscognitive.com

  • 7 day risk free free trial

References

[1] Sayour A, Tokodi M, Celeng C, Takx R, Fábián A, Lakatos B, Friebel R, Surkova E, Merkely B, Kovács A. Superior prognostic value of three-dimensional echocardiography-derived right ventricular ejection fraction: a meta-analysis. medRxiv (pre-print); doi: https://doi.org/10.1101/2022.06.02.22275907

[2] Surkova E, Muraru D, Genovese D, Aruta P, Palermo C, Badano LP. Relative Prognostic Importance of Left and Right Ventricular Ejection Fraction in Patients With Cardiac Diseases. J Am Soc Echocardiogr. 2019 Nov;32(11):1407-1415.e3. doi: 10.1016/j.echo.2019.06.009. Epub 2019 Aug 7. PMID: 31400846.

[3] Tokodi M, Németh E, Lakatos BK, Kispál E, Tősér Z, Staub L, Rácz K, Soltész Á, Szigeti S, Varga T, Gál J, Merkely B, Kovács A. Right ventricular mechanical pattern in patients undergoing mitral valve surgery: a predictor of post-operative dysfunction? ESC Heart Fail. 2020 Jun;7(3):1246-1256. doi: 10.1002/ehf2.12682. Epub 2020 Mar 26. PMID: 32220010; PMCID: PMC7261576.

[4] Surkova E, Kovács A, Tokodi M, Lakatos BK, Merkely B, Muraru D, Ruocco A, Parati G, Badano LP. Contraction Patterns of the Right Ventricle Associated with Different Degrees of Left Ventricular Systolic Dysfunction. Circ Cardiovasc Imaging. 2021 Oct;14(10):e012774. doi: 10.1161/CIRCIMAGING.121.012774. Epub 2021 Sep 30. PMID: 34587749; PMCID: PMC8522626.