Argus Cognitive makes intelligent medical instruments,
delivered as SaaS, regulated by the FDA

About us

We are creating Analytics-as-a-Service solutions to aid diagnosis or therapy choices. We are primarily interested in the dual challenges of 1) earlier and more granular diagnosis and 2) improved therapy selection for individual patients.

We focus on narrowly defined situations where a clinical decision is “costly”, on account of requiring the generation, collation and processing of large volumes of complex data by highly-trained experts. Good examples for such scenarios include the diagnosis of autism based on a scripted interview or the detection of certain types of heart disease based on an echocardiogram.

For such cases we develop automated, scalable medical decision support systems that receive raw data and produce a recommendation for diagnosis or therapy. Our products are available as Analytics-as-a-Service, and regulated as medical devices.

Ultimately, our solutions help health care providers select therapies for individual patients that benefit them the most. If we do our job well, we improve patient care, increase the success rate of therapies and eliminate unnecessary cost associated with suboptimal therapy choices.


We develop virtual medical instruments, powered by a proprietary fleet of intelligent virtual sensors. Our technology comprehensively quantifies organ-level, system-level and patient-level function. This allows medical professionals to make better, more informed clinical decisions. Our products are regulated as medical devices, and are delivered as software as a service.

Too often medical professionals must choose between quantitative information that is limited in scope, and qualitative information that is comprehensive. Our technology delivers quantified, comprehensive data.


We have active product development programs that address a variety of important medical areas. Our first two products entering the FDA approval process are:

1. ReVISION: Award-winning analysis of right ventricle mechanics to detect and predict a range of debilitating cardiac conditions, such as certain types or heart failure, pulmonary hypertension, and more.

2. ARGUS-MDS-ASD (working name): Analysis of social communication skills based on video and audio recordings during scripted psychological interviews to support a) autism diagnosis and b) response to therapy.


Behavioral Health

  • Predicting the ADOS-2 Calibrated Severity Score From Video And Audio Analysis

    Andras Sarkany, Khaleel Kamal, Emily Dillon, Edith Ocampo, Sarely Licona, Allie Wainer, Latha Soorya, Zoltan Toser

    INSAR - International Society for Autism Research / Annual Meeting


    Ongoing strides in robust non-intrusive methods allow for the application of computational behavioral assessments in clinical settings, mitigating tedious manual coding processes. Using machine learning components, automated behavioral assessment aims to facilitate the detailed coding of naturalistic behavior (including prosody, facial landmarks, gaze, and pose estimations)...

  • Advancements in vision & speech analyses of ASD symptom domains

    Zoltán Tősér, Zachary Arnold, Richard Bellon, Máté Csákvári, Edith Ocampo, Allison Wainer, Mark Pollack, András Lőrincz, Latha Soorya

    INSAR - International Society for Autism Research / Annual Meeting


    The mission of Argus Cognitive is to develop a non-intrusive, fully automated system that increases accessibility, affordability and objectivity of behavioral health care for common mental health and neurological conditions...

  • Towards an automated analysis of social-communication behaviors in ASD

    Zoltán Tősér, Zachary Arnold, Máté Csákvári, András Lőrincz, Edith Ocampo, Mark Pollack, Allison Wainer, Latha Soorya

    INSAR - International Society for Autism Research / Annual Meeting


    Objective behavioral assessment is a mainstay of behavioral sciance tools. Recent advances adapting human-AI interaction technology has promise to streamline analisys of core social-communication behaviors for treatment research...


  • Assessment of Right Ventricular Mechanics by 3D Transesophageal Echocardiography in the Early Phase of Acute Respiratory Distress Syndrome

    Bruno Evrard, Bálint Károly Lakatos, Marine Goudelin, Zoltán Tősér, Béla Merkely, Philippe Vignon and Attila Kovács

    Frontiers in Cardiovascular Medicine


    Aim: To compare global and axial right ventricular ejection fraction in ventilated patients for moderate-to-severe acute respiratory distress syndrome (ARDS) secondary to early SARS-CoV-2 pneumonia or to other causes, and in ventilated patients without ARDS used as reference.

  • Biventricular mechanical pattern of the athlete's heart: comprehensive characterization using three-dimensional echocardiography

    Alexandra Fábián, Adrienn Ujvári, Márton Tokodi, Bálint Károly Lakatos, Orsolya Kiss, Máté Babity, Márk Zámodics, Nóra Sydó, Emese Csulak, Hajnalka Vágó, Liliána Szabó, Anna Réka Kiss, Andrea Szűcs, Béla Merkely, Attila Kovács

    European Journal of Preventive Cardiology


    While left ventricular (LV) adaptation to regular, intense exercise has been thoroughly studied, data concerning the right ventricular (RV) mechanical changes and their continuum with athletic performance are scarce. The aim of this study was to characterize biventricular morphology and function and their relation to sex, age, and sports classes in a large cohort of elite athletes using three-dimensional (3D) echocardiography.

  • Prognostic Value of Right Ventricular Strains Using Novel Three-Dimensional Analytical Software in Patients With Cardiac Disease

    Tetsuji Kitano, Attila Kovács, Yosuke Nabeshima, Márton Tokodi, Alexandra Fábián, Bálint Károly Lakatos and Masaaki Takeuchi

    Frontiers in Cardiovascular Medicine


    Right ventricular (RV) three-dimensional (3D) strains can be measured using novel 3D RV analytical software (ReVISION). Our objective was to investigate the prognostic value of RV 3D strains.

  • Post-marathon Decline in Right Ventricular Radial Motion Component Among Amateur Sportsmen

    Zuzanna Lewicka-Potocka, Anna Maria Kaleta-Duss, Ewa Lewicka, Marcin Kubik, Anna Faran, Paweł Szymeczko, Rafał Gała̧ska, Grzegorz Raczak and Alicja Da̧browska-Kugacka

    Frontiers in Physiology


    Moderate physical activity has a positive impact on health, although extreme forms of sport such as marathon running may trigger exercise-induced cardiac fatigue. The explicit distinction between the right ventricular (RV) physiological response to training and maladaptive remodeling has not yet been determined. In this study, we aimed to analyze the impact of running a marathon on RV mechanics in amateur athletes using three-dimensional (3D) echocardiography (ECHO) and the ReVISION method (RV separate wall motion quantification).

  • Contraction patterns of the systemic right ventricle: a three-dimensional echocardiography study

    Elena Surkova, Attila Kovács, Bálint Károly Lakatos, Márton Tokodi, Alexandra Fábián, Cathy West, Roxy Senior, Wei Li

    European Heart Journal-Cardiovascular Imaging


    Aims: To investigate contraction patterns of the systemic right ventricle (SRV) in patients with transposition of great arteries (TGA) post-atrial switch operation and with congenitally corrected transposition of great arteries (ccTGA).

  • Contraction Patterns of the Right Ventricle Associated with Different Degrees of Left Ventricular Systolic Dysfunction

    Elena Surkova, Attila Kovács, Márton Tokodi, Bálint Károly Lakatos, Béla Merkely, Denisa Muraru, Alessandro Ruocco, Gianfranco Parati, Luigi P. Badano

    Circulation: Cardiovascular Imaging


    The functional adaptation of the right ventricle (RV) to the different degrees of left ventricular (LV) dysfunction remains to be clarified. We sought to (1) assess the changes in RV contraction pattern associated with the reduction of LV ejection fraction (EF) and (2) analyze whether the assessment of RV longitudinal, radial, and anteroposterior motion components of total RVEF adds prognostic value.

  • Global and regional right ventricular mechanics in repaired tetralogy of Fallot with chronic severe pulmonary regurgitation: a three-dimensional echocardiography study

    Jurate Bidviene, Denisa Muraru, Attila Kovacs, Bálint Lakatos, Egle Ereminiene, Csilla Liptai, Jolanta-Justina Vaskelyte, Remigijus Zaliunas, Elena Surkova & Luigi P. Badano

    Cardiovascular Ultrasound


    Data about the right ventricular (RV) mechanics adaptation to volume overload in patients with repaired tetralogy of Fallot (rToF) are limited. Accordingly, we sought to assess the mechanics of the functional remodeling occurring in the RV of rToF with severe pulmonary regurgitation.

  • Anteroposterior Contraction of the Systemic Right Ventricle: Underrecognized Component of the Global Systolic Function

    Elena Surkova, Attila Kovács, Bálint Károly Lakatos, Wei Li

    Case Reports


    Accurate echocardiographic evaluation of the systemic right ventricle is challenging because of its specific morphology and contraction patterns. We present a detailed multimodality assessment of the systemic right ventricle, analyze the relative contribution of the longitudinal, radial, and anteroposterior components of systolic function, and identify reasons for a potential discrepancy among imaging modalities...

  • Partitioning the Right Ventricle Into 15 Segments and Decomposing Its Motion Using 3D Echocardiography-Based Models: The Updated ReVISION Method

    Márton Tokodi, Levente Staub, Ádám Budai, Bálint Károly Lakatos, Máté Csákvári, Ferenc Imre Suhai, Liliána Szabó, Alexandra Fábián, Hajnalka Vágó, Zoltán Tősér, Béla Merkely and Attila Kovács

    Frontiers in Cardiovascular Medicine


    Three main mechanisms contribute to global right ventricular (RV) function: longitudinal shortening, radial displacement of the RV free wall (bellows effect), and anteroposterior shortening (as a consequence of left ventricular contraction)...

  • Sex-Specific Patterns of Mortality Predictors Among Patients Undergoing Cardiac Resynchronization Therapy: A Machine Learning Approach

    Márton Tokodi, Anett Behon, Eperke Dóra Merkel, Attila Kovács, Zoltán Tősér, András Sárkány, Máté Csákvári, Bálint Károly Lakatos, Walter Richard Schwertner, Annamária Kosztin, Béla Merkely

    Frontiers in Cardiovascular Medicine


    The relative importance of variables explaining sex differences in outcomes is scarcely explored in patients undergoing cardiac resynchronization therapy (CRT). We sought to implement and evaluate machine learning (ML) algorithms for the prediction of 1- and 3-year all-cause mortality in CRT patients...

  • Regional shape, global function and mechanics in right ventricular volume and pressure overload conditions: a three‐dimensional echocardiography study

    Jurate Bidviene, Denisa Muraru, Francesco Mafessanti, Egle Ereminiene, Attila Kovács, Bálint Lakatos, Jolanta‐Justina Vaskelyte, Remigijus Zaliunas, Elena Surkova, Gianfranco Parati, Luigi P. Badano

    The International Journal of Cardiovascular Imaging


    Our aim was to assess the regional right ventricular (RV) shape changes in pressure and volume overload conditions and their relations with RV function and mechanics. The end-diastolic and end-systolic RV endocardial surfaces were analyzed with three-dimensional echocardiography (3DE)...

  • Acute changes of global and longitudinal right ventricular function: an exploratory analysis in patients undergoing open-chest mitral valve surgery, percutaneous mitral valve repair and off-pump coronary artery bypass grafting

    Marius Keller, Tim Heller, Tobias Lang, Johannes Patzelt, Juergen Schreieck, Christian Schlensak, Peter Rosenberger and Harry Magunia

    Cardiovascular Ultrasound


    Right ventricular (RV) function is an important prognostic indicator. The acute effects of cardiac interventions or cardiac surgery on global and longitudinal RV function are not entirely understood. In this study, acute changes of RV function during mitral valve surgery (MVS),...

  • The ongoing quest for improving machine learning-based risk stratification

    Márton Tokodi, Walter Richard Schwertner, Annamária Kosztin, Béla Merkely

    European Heart Journal


    This commentary refers to ‘Machine learning-based mortality prediction: how to be connected to daily clinical practice?’, by W.H. Kim and J.-T. Kim, on page 2913. We greatly appreciate the interest of Kim and Kim in our recently published work.1,2 As pointed out by them, the current version of the SEMMELWEIS-CRT score has some limitations besides its undeniable strengths...

  • Right ventricular mechanical pattern in patients undergoing mitral valve surgery: a predictor of post-operative dysfunction?

    Márton Tokodi, Endre Németh, Bálint K. Lakatos, Erika Kispál, Zoltán Tősér, Levente Staub, Kristóf Rácz, Ádám Soltész, Szabolcs Szigeti, Tamás Varga, János Gál, Béla Merkely and Attila Kovács

    ESC Heart Failure


    The PREPARE-MVR study (PRediction of Early PostoperAtive Right vEntricular failure in Mitral Valve Replacement/Repair patients) sought to investigate the alterations of right ventricular (RV) contraction pattern in patients undergoing mitral valve replacement/repair (MVR) and to explore the associations between pre-operative RV mechanics and early post-operative RV dysfunction (RVD)...

  • Competing Approaches to Defining Right Ventricular Motion Directions in Three Dimensions: A Pressing Need for Standardization?

    Márton Tokodi, MD, Bálint Károly Lakatos, MD, Zoltán Tősér, Msc, Béla Merkely, MD, PhD, DSc, Masaaki Takeuchi, MD, PhD, FASE, Attila Kovács, MD, PhD, FASE

    Journal of the American Society of Echocardiography


    We greatly appreciate the interest and insightful comments of Duchateau et al. regarding our work. Indeed, the standardized alignment of three-dimensional (3D) models is the linchpin of all technologies aiming to evaluate right ventricular (RV) function in a directionwise manner as variations in the definition of directions might significantly affect the measured parameters...

  • Importance of Nonlongitudinal Motion Components in Right Ventricular Function: Three-Dimensional Echocardiographic Study in Healthy Volunteers

    Bálint Károly Lakatos, MD, Yosuke Nabeshima, MD, Márton Tokodi, MD, Yasufumi Nagata, MD, PhD, Zoltan Tősér, MSc, Kyoko Otani, MD, PhD, Tetsuji Kitano, MD, Alexandra Fábián, MD, Adrienn Ujvári, MD, Andras Mihály Boros, MD, PhD, Béla Merkely, MD, PhD, DSc, Attila Kovács, MD, PhD, FASE, and Masaaki Takeuchi, MD, PhD, FASE

    Journal of the American Society of Echocardiography


    Global right ventricular (RV) function is determined by the interplay of different motion compo- nents related to the myofiber architecture, and the relative importance of these components is still not thoroughly characterized. The aims of this study were to quantify the relative contributions of longitudinal, radial, and anteroposterior motion components...

  • Machine learning-based mortality prediction of patients undergoing cardiac resynchronization therapy: the SEMMELWEIS-CRT score

    Márton Tokodi, Walter Richard Schwertner, Attila Kovács, Zoltán Tősér, Levente Staub, András Sárkány, Bálint Károly Lakatos, Anett Behon, András Mihály Boros, Péter Perge, Valentina Kutyifa, Gábor Széplaki, László Gellér, Béla Merkely, and Annamária Kosztin

    European Heart Journal


    Our aim was to develop a machine learning (ML)-based risk stratification system to predict 1-, 2-, 3-, 4-, and 5- year all-cause mortality from pre-implant parameters of patients undergoing cardiac resynchronization therapy (CRT)...

  • Right ventricular mechanical pattern in health and disease: beyond longitudinal shortening

    Attila Kovács, Bálint Lakatos, Márton Tokodi, Béla Merkely

    Heart Failure Reviews


    Right ventricular (RV) function has proven to be a prognostic factor in heart failure with reduced and preserved ejection fraction and in pulmonary hypertension. RV function is also a cornerstone in the management of novel clinical issues, such as mechanical circulatory support devices or grown-up congenital heart disease patients...

  • Exercise-induced shift in right ventricular contraction pattern: novel marker of athlete’s heart?

    Bálint Károly Lakatos, Orsolya Kiss, Márton Tokodi, Zoltán Tősér, Nóra Sydó, Gergő Merkely, Máté Babity, Mónika Szilágyi, Zsuzsanna Komócsin, Csaba Bognár, Attila Kovács, and Béla Merkely

    American Journal of Physiology-Heart and Circulatory Physiology


    Regular vigorous physical exercise results in significant changes in cardiac morphology and function, commonly referred as the athlete’s heart. According to different sport disciplines, training regime, level of competition, age, sex, and even genetic factors, the athlete’s heart represents a broad spectrum of physiological cardiac alterations...

  • Response to Ivey-Miranda and Farrero-Torres “Is there dominance of free wall radial motion in global right ventricular function in heart transplant recipients or in all heart surgery patients?”

    Attila Kovács, Bálint Lakatos, Endre Németh, Béla Merkely

    Clinical Transplantation


    In our original article — recently published in Clinical Transplantation — we concluded that after orthotopic heart transplantation, the radial motion of right ventricular free wall compensates for the decreased longitudinal shortening to maintain ejection fraction. The editorial from Ivey-Miranda and Farrero-Torres questioned...

  • Dominance of free wall radial motion in global right ventricular function of heart transplant recipients

    Bálint Károly Lakatos, Márton Tokodi, Alexandra Assabiny, Zoltán Tősér, Annamária Kosztin, Alexandra Doronina, Kristóf Rácz, Kinga Bianka Koritsánszky, Viktor Berzsenyi, Endre Németh, Balázs Sax, Attila Kovács, Béla Merkely

    Clinical Transplantation


    Assessment of right ventricular (RV) function using conventional echocardiography might be inadequate as the radial motion of the RV free wall is often neglected. Our aim was to quantify the longitudinal and the radial components of RV function using three-dimensional (3D) echocardiography in heart transplant (HTX) recipients...

  • Quantification of the relative contribution of the different right ventricular wall motion components to right ventricular ejection fraction: the ReVISION method

    Bálint Lakatos, Zoltán Tősér, Márton Tokodi, Alexandra Doronina, Annamária Kosztin, Denisa Muraru, Luigi P. Badano, Attila Kovács and Béla Merkely

    Cardiovascular Ultrasound


    Three major mechanisms contribute to right ventricular (RV) pump function: (i) shortening of the longitudinal axis with traction of the tricuspid annulus towards the apex; (ii) inward movement of the RV free wall; (iii) bulging of the interventricular septum into the RV and stretching the free wall over the septum...


Argus Cognitive was founded in 2016 by computer scientists, psychologists and a medical device entrepreneur.

  • Zoltan Toser (CEO) and Andras Lorincz (CSO) are computer scientists, specializing in machine learning.

  • Mark Pollack, MD and Latha Soorya, PhD are a practicing psychiatrist and a clinical psychologist.

  • Attila Meretei, MD has been developing medical devices for almost 20 years.

Our product development team is located in Budapest, Hungary.

We maintain a symbiotic relationship with the Neural Information Processing Group at Eotvos Lorand University, Budapest, Hungary, where we can test new technologies before including them in our development pipeline.

In cardiology we closely collaborate with various researchers in the US and Europe.

We are hiring

We are always on the lookout for talented people to join our team. We have openings in the following positions:

Our team is geographically dispersed, present in three continents, so provided you have excellent communication skills, remote work is feasible. Needless to say, good English is a must.

If all this sounds interesting, or you would like more info, don't hesitate to reach out to us at If you like our company but don't think you fit into the roles above, don't worry. Get in touch with us, and let's see if we can figure something out together. We are flexible.


We have a lot more to say about the company and the team, the unmet need, the market, our technology and products, clinical results and regulatory plans and opportunities in other fields of medicine. If you are interested in a dialogue, collaboration or joining our team, please reach out to us. Thank you!

Zoltan Toser

CEO, Argus Cognitive, Inc.

+1 603 322 1944

Attila Meretei, MD

President, Argus Cognitive, Inc.

+1 603 400 2440

Dartmouth Regional Technical Center, 16 Cavendish Court, Lebanon, NH 03766